Development of Selective DNA-Interacting Ligands: Understanding the Function of Non-canonical DNA Structures by Sefan Asamitsu
Requirements: .ePUB reader, 33.2 MB
Overview: This book addresses the development of both DNA-sequence-selective and DNA-form-selective ligands, with the aim of creating potential molecular probes and therapeutic agents for non-canonical DNA structure-caused human diseases.
Over the past two decades, the structural diversity of DNA forms has been proven to have profound implications in various biological, neurological, and pharmacological events. In response, researchers have since made tremendous efforts to obtain highly active drugs interacting with disease-related non-canonical DNA structures. These drugs, however, have not yet been approved for clinical use. One obstacle impeding their clinical application has to do with selectivity.
Genre: Non-Fiction > Health, Fitness & Self-help
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