The Power of Prions: The Strange and Essential Proteins That Can Cause Alzheimer’s, Parkinson’s, and Other Diseases by Michel Brahic
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Overview: The remarkable family of proteins that can make us very ill—but can also be linked to long-term memory, immunity, and the origin of life
Over the last decade, scientists have discovered the importance and widespread presence in the body of a remarkable family of proteins known as prion proteins. Research links various types of prion proteins to neurodegenerative diseases such as Parkinson’s and Alzheimer’s—and this has fueled the search for new drugs that could halt the progression of these terrible disorders. Other discoveries have revealed the essential roles prion proteins play in memory and immunity, and—in an extraordinary finding—the part they may have played in the beginnings of life on our planet. In this engaging and accessible book, Michel Brahic tells the story of these amazing and versatile proteins.
Brahic, a leading researcher on diseases of the central nervous system, first describes the discovery of prions and their role in infection, beginning with early work on the animal disease scrapie and a mysterious human illness in New Guinea, apparently transmitted by cannibalism. Prions were eventually identified and named by Stanley Prusiner in the 1980s. (Brahic tells us Prusiner’s alternate name for prion was “piaf.”) Prion proteins were then revealed as the cause of other illnesses, from “mad cow” disease and its human counterpart, Creutzfeldt-Jakob disease, to such noninfectious brain disorders as Parkinson’s and Alzheimer’s. While the prion proteins responsible for diseases are definitively “bad,” Brahic also explains that these abnormal prions are rare exceptions. Most of the time, prion proteins actually serve “good” and vital functions—and they may even have been present at the origin of life itself.
Genre: Non-Fiction > Educational
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Category: Educational
Download Decision Mathematics by Wan Fairos Wan Yaacob (.PDF)
Decision Mathematics, Statistical Learning and Data Mining: Selected Contributions from ICMSCT2023, Manila, Philippines, September 20-21 by Wan Fairos Wan Yaacob, Yap Bee Wah, Obaid Ullah Mehmood
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Overview: This book is a collection of selected research papers presented at the Mathematics, Statistics and Computing Technology (ICMSCT2023), held at the UST Angelicum College, Philippines, from 20th to 21st September 2023. This biennial event is a result from collaborations of university partners in Malaysia, Thailand, Indonesia and Philippines.
Genre: Non-Fiction > Educational
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Requirements: .PDF reader, 20.3 MB True PDF
Overview: This book is a collection of selected research papers presented at the Mathematics, Statistics and Computing Technology (ICMSCT2023), held at the UST Angelicum College, Philippines, from 20th to 21st September 2023. This biennial event is a result from collaborations of university partners in Malaysia, Thailand, Indonesia and Philippines.
Genre: Non-Fiction > Educational
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Download NATO and the War in Ukraine by Jan Eichler (.ePUB)+
NATO and the War in Ukraine: Geopolitical Context and Long-term Consequences by Jan Eichler (Contributions to International Relations)
Requirements: .PDF/.ePUB reader, 5 mb
Overview: This book presents a fresh perspective on the geopolitical landscape surrounding NATO’s enlargement, aptly termed "expansion by invitation." Looking beyond conventional narratives, it unravels the multifaceted outcomes of this process, extending beyond the initial optimism.
While acknowledging the merits of NATO’s expansion, the book scrutinizes its contentious side effects, notably the escalating militarization of the Baltic and Black Sea regions, heightened military expenditure, shifts toward offensive doctrines, and the surge in military exercises and incidents between NATO and Russia. In a world witnessing a renewed bipolarization akin to the Cold War era, the book underscores the need for NATO and Russia to de-escalate tensions and strive towards a transition from contemporary negative peace to a more constructive, positive peace.
Devoid of bias, this book refrains from condemning the expansion process but rather calls for an acknowledgment of its consequences. It is an indispensable resource for academics seeking a nuanced understanding of NATO’s expansion, challenging prevailing terminologies and offering insights into the complex dynamics of international security in Europe.
Genre: Non-Fiction > Educational
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Requirements: .PDF/.ePUB reader, 5 mb
Overview: This book presents a fresh perspective on the geopolitical landscape surrounding NATO’s enlargement, aptly termed "expansion by invitation." Looking beyond conventional narratives, it unravels the multifaceted outcomes of this process, extending beyond the initial optimism.
While acknowledging the merits of NATO’s expansion, the book scrutinizes its contentious side effects, notably the escalating militarization of the Baltic and Black Sea regions, heightened military expenditure, shifts toward offensive doctrines, and the surge in military exercises and incidents between NATO and Russia. In a world witnessing a renewed bipolarization akin to the Cold War era, the book underscores the need for NATO and Russia to de-escalate tensions and strive towards a transition from contemporary negative peace to a more constructive, positive peace.
Devoid of bias, this book refrains from condemning the expansion process but rather calls for an acknowledgment of its consequences. It is an indispensable resource for academics seeking a nuanced understanding of NATO’s expansion, challenging prevailing terminologies and offering insights into the complex dynamics of international security in Europe.
Genre: Non-Fiction > Educational
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Download Knack American Sign Language by Suzie Chafin (.ePUB)
Knack American Sign Language: A Step-By-Step Guide To Signing by Suzie Chafin (Knack: Make It Easy)
Requirements: .ePUB reader, 16 mb
Overview: While learning a new language isn’t a “knack” for everyone, Knack American Sign Language finally makes it easy. The clear layout, succinct information, and topic-specific sign language partnered with high-quality photos enable quick learning. By a “bilingual” author whose parents were both deaf, and photographed by a design professor at the leading deaf university, Gallaudet, it covers all the basic building blocks of communication. It does so with a view to each reader’s reason for learning, whether teaching a toddler basic signs or communicating with a deaf coworker. Readers will come away with a usable knowledge base rather than a collection of signs with limited use.
Genre: Non-Fiction > Educational
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Requirements: .ePUB reader, 16 mb
Overview: While learning a new language isn’t a “knack” for everyone, Knack American Sign Language finally makes it easy. The clear layout, succinct information, and topic-specific sign language partnered with high-quality photos enable quick learning. By a “bilingual” author whose parents were both deaf, and photographed by a design professor at the leading deaf university, Gallaudet, it covers all the basic building blocks of communication. It does so with a view to each reader’s reason for learning, whether teaching a toddler basic signs or communicating with a deaf coworker. Readers will come away with a usable knowledge base rather than a collection of signs with limited use.
Genre: Non-Fiction > Educational
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Download The Oxford Handbook of the Books of Kings by Steven L. McKenzie (.PDF)
The Oxford Handbook of the Books of Kings by Steven L. McKenzie
Requirements: .PDF reader, 17.11 MB | True PDF |
Overview: The Books of Kings have long been at the center of scholarly discussions on the Hebrew Bible because they constitute important sources for the history of ancient Israel and Judah, and because they are key components of the Deuteronomistic History. The Oxford Handbook of the Books of Kings provide a clear and useful introduction to the main aspects and issues pertaining to the scholarly study of Kings. These include textual history (including the linguistic profile), compositional history, literary approaches, key characters, history, important recurring themes, reception history and some contemporary readings. As a one-volume introduction embracing all the aspects of the study of Kings, written by an international and diverse team of scholars, this handbook is the ideal point of entry into the study of Kings for generations of students and scholars.
Genre: Non-Fiction > Educational
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Requirements: .PDF reader, 17.11 MB | True PDF |
Overview: The Books of Kings have long been at the center of scholarly discussions on the Hebrew Bible because they constitute important sources for the history of ancient Israel and Judah, and because they are key components of the Deuteronomistic History. The Oxford Handbook of the Books of Kings provide a clear and useful introduction to the main aspects and issues pertaining to the scholarly study of Kings. These include textual history (including the linguistic profile), compositional history, literary approaches, key characters, history, important recurring themes, reception history and some contemporary readings. As a one-volume introduction embracing all the aspects of the study of Kings, written by an international and diverse team of scholars, this handbook is the ideal point of entry into the study of Kings for generations of students and scholars.
Genre: Non-Fiction > Educational
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